COVID vaccinations: Spike proteins in the cell nucleus and DNA damage detected

The Corona virus (SARS-CoV-2) has kept people on tenterhooks for almost two years now. The resulting pandemic has not only severely affected the global economy, but also claimed many lives. Since then, scientists around the world have been feverishly researching a suitable treatment option.

The COVID vaccine, which was used for the first time in December 2020, quickly became a beacon of hope for a return to normality. But the mRNA vaccination, which was used for the first time, is very different from the vaccinations used so far and is not without controversy. While a conventional vaccination immunises the human body by administering the respective killed pathogen, the COVID vaccination transcribes the DNA (i.e. the human genetic material) in the cell nucleus into mRNA. The mRNA contains the blueprint for the so-called spike protein. This spike protein is the reason why people infected with COVID develop symptoms.

The COVID vaccination is supposed to form antibodies against the spike protein and thus protect people from COVID infection - at least that is the plan. However, a study by scientists at Stockholm University published in October 2021 showed that the spike proteins can penetrate into the cell nucleus and cause lasting damage to the DNA there.

What role do spike proteins play in COVID-19 infection?

The so-called spike protein is specifically used by the Sars-CoV-2 pathogen to dock onto human cells and in this way introduce the COVID virus into the cells. This conclusion was already reached by researchers who carried out initial in vitro investigations on human cells and found spike proteins in the cells of people severely infected with Corona in particular. The study by scientists at Stockholm University also showed that the spike protein damages the DNA's ability to repair itself. This also explains the severe COVID courses, as the spike protein impairs the natural immune system.

Within the corona vaccine, however, the spike protein takes on a not insignificant role. The Covid 19 vaccine carries the blueprint for the spike protein of the Corona virus. By means of a code, the COVID vaccination is supposed to reproduce the spike protein and thus stimulate its production in order to induce immunisation. In their study, researchers from Stockholm University have shown the potential side effects of this spike protein-based vaccine.

DNA repair system impaired by COVID vaccination

The Department of Clinical Microbiology and Virology at Umeå University and the molecular biologists at the Department of Molecular Biosciences at Stockholm University found out in their research that the spike proteins can permanently damage the functioning of the DNA. In particular, the ability to repair itself is affected by the spike protein.

Alongside the body's own immune system, this DNA repair system is an important protective mechanism against infectious diseases. This is because the formation of white blood cells, the so-called B and T cells, is essential for effectively fighting an infection. The B and T cells are, so to speak, the white blood cells of the immune system. Both DNA and the immune system are crucially involved in the formation of white blood cells. If too few white blood cells are produced or if the B and T cells are inhibited in their growth, this leads to an immune deficiency. An intact immune system in turn promotes the development of infectious diseases.

DNA damage through COVID vaccination?

The researchers of the Stockholm study claim to have come to exactly this conclusion, namely that the spike protein undermines the DNA repair system and the adaptive human immune system in vitro. The COVID vaccination would thus set in motion a mechanism that, through the formation of the spike proteins, would allow the body's own immunity to be impaired by lowering DNA repair. Especially in older people or in people with an already weakened immune system, this circumstance can have devastating effects and lead to severe COVID-19 courses.

Increased tumour formation possible

The ability of DNA to repair itself is not only important for the body's own immune system. DNA is also capable of repairing any errors, so-called mutations, itself. If this function is disrupted by a defective DNA repair system, mutations may not even be recognised and thus cannot be repaired. Too many mutations, in turn, lead to tumours or genetic diseases.

Since the researchers at Stockholm University see the DNA repair system impaired by the formation of the spike protein, they fear that the COVID vaccination could contribute to increased tumour formation.

What consequences should be drawn from the Stockholm study?

The researchers from Stockholm University see serious side effects from the production of complete spike proteins by the COVID vaccination. They therefore suggest instead that only certain parts of the spike protein should be used in the COVID vaccination in future. If the complete spike protein is not produced, they hope that the vaccination will be safer and more effective.

The Stockholm study - A summary

The Sars-CoV-2 agent of the covid virus uses the so-called spike protein to dock onto human cells and in this way introduce the COVID virus into the cells. The Covid 19 vaccine carries the blueprint for the spike protein of the Corona virus in the form of a code. In this way, the spike protein is supposed to be replicated and its production stimulated in order to establish natural immunity to COVID.

However, researchers at Stockholm University recently found that the spike protein also affects the DNA repair system. Along with the body's own immune system, this is one of the most important human protective mechanisms against infectious diseases. This is because the DNA is decisively involved in the formation of B and T cells, the so-called white blood cells of the immune system. If a person does not form enough white blood cells, this leads to an immune deficiency.

In addition to the formation of white blood cells, the DNA also has the ability to recognise and repair so-called mutants, i.e. errors in the DNA. The spike protein virtually disables this DNA repair system. As a result, mutants can, if necessary, neither be recognised nor repaired. However, the formation of mutants leads to increased tumour formation or the development of genetic diseases.

Here is the link to the study: viruses-13-02056-v2-1